Analyzing the Release of Copeptin from the Heart in Acute Myocardial Infarction Using a Transcoronary Gradient Model

نویسندگان

  • Jes-Niels Boeckel
  • Jana Oppermann
  • Remzi Anadol
  • Stephan Fichtlscherer
  • Andreas M. Zeiher
  • Till Keller
چکیده

Copeptin is the C-terminal end of pre-provasopressin released equimolar to vasopressin into circulation and recently discussed as promising cardiovascular biomarker amendatory to established markers such as troponins. Vasopressin is a cytokine synthesized in the hypothalamus. A direct release of copeptin from the heart into the circulation is implied by data from a rat model showing a cardiac origin in hearts put under cardiovascular wall stress. Therefore, evaluation of a potential release of copeptin from the human heart in acute myocardial infarction (AMI) has been done.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2016